Toxicidad de Macroquistes de Sarcocystis aucheniae H. Wild en Ratones Domésticos (Mus musculus)

Carhuapoma D. Víctor; Valencia M. Nicasio; Sanchez A. Víctor

doi:10.15381/rivep.v27i3.11988

Toxicidad de Macroquistes de Sarcocystis aucheniae H. Wild en Ratones Domésticos (Mus musculus)

Translated title of the contribution: Toxic effect of macrocysts of sarcocystis aucheniae H. Wild in house mice

Carhuapoma D. Víctor
, Valencia M. Nicasio
, Sanchez A. Víctor

Centro de Investigación Científica Multidisciplinario de Ingeniería

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of the study was to determine the toxicity of lysate macrocysts inoculum of Sarcocystis aucheniae (LMSA) in house mice (n=36) at concentrations of 5 and 10% (0, 50 and 100 mg of protein per gram of body weight) in doses of 0.5 and 1.0 ml. Rectal temperature, respiratory rate and survival rate plus histopathological changes in liver, kidney, heart, and lung were evaluated. All treated mice died within 4 to 20 hours after inoculation, showing hypothermia, dyspnea and bradypnea. The kidney and liver were most affected organs, showing severe hyperemia, tissue degeneration and hyperplasia. The mice in the control group showed no visible abnormalities or death. The results showed toxicity and lethality due to the lysate macrocysts inoculum of Sarcocystis aucheniae in house mice.

Translated title of the contribution	Toxic effect of macrocysts of sarcocystis aucheniae H. Wild in house mice
Original language	Spanish
Pages (from-to)	589-594
Number of pages	6
Journal	Revista de Investigaciones Veterinarias del Peru
Volume	27
Issue number	3
DOIs	https://doi.org/10.15381/rivep.v27i3.11988
State	Published - 1 Jul 2016

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10.15381/rivep.v27i3.11988

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title = "Toxicidad de Macroquistes de Sarcocystis aucheniae H. Wild en Ratones Dom{\'e}sticos (Mus musculus)",

abstract = "The aim of the study was to determine the toxicity of lysate macrocysts inoculum of Sarcocystis aucheniae (LMSA) in house mice (n=36) at concentrations of 5 and 10\% (0, 50 and 100 mg of protein per gram of body weight) in doses of 0.5 and 1.0 ml. Rectal temperature, respiratory rate and survival rate plus histopathological changes in liver, kidney, heart, and lung were evaluated. All treated mice died within 4 to 20 hours after inoculation, showing hypothermia, dyspnea and bradypnea. The kidney and liver were most affected organs, showing severe hyperemia, tissue degeneration and hyperplasia. The mice in the control group showed no visible abnormalities or death. The results showed toxicity and lethality due to the lysate macrocysts inoculum of Sarcocystis aucheniae in house mice.",

keywords = "Inoculum, Lethality, Macrocystis, Mouse, Sarcocystis",

author = "V{\'i}ctor, \{Carhuapoma D.\} and Nicasio, \{Valencia M.\} and V{\'i}ctor, \{Sanchez A.\}",

year = "2016",

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doi = "10.15381/rivep.v27i3.11988",

language = "Espa{\~n}ol",

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TY - JOUR

T1 - Toxicidad de Macroquistes de Sarcocystis aucheniae H. Wild en Ratones Domésticos (Mus musculus)

AU - Víctor, Carhuapoma D.

AU - Nicasio, Valencia M.

AU - Víctor, Sanchez A.

PY - 2016/7/1

Y1 - 2016/7/1

N2 - The aim of the study was to determine the toxicity of lysate macrocysts inoculum of Sarcocystis aucheniae (LMSA) in house mice (n=36) at concentrations of 5 and 10% (0, 50 and 100 mg of protein per gram of body weight) in doses of 0.5 and 1.0 ml. Rectal temperature, respiratory rate and survival rate plus histopathological changes in liver, kidney, heart, and lung were evaluated. All treated mice died within 4 to 20 hours after inoculation, showing hypothermia, dyspnea and bradypnea. The kidney and liver were most affected organs, showing severe hyperemia, tissue degeneration and hyperplasia. The mice in the control group showed no visible abnormalities or death. The results showed toxicity and lethality due to the lysate macrocysts inoculum of Sarcocystis aucheniae in house mice.

AB - The aim of the study was to determine the toxicity of lysate macrocysts inoculum of Sarcocystis aucheniae (LMSA) in house mice (n=36) at concentrations of 5 and 10% (0, 50 and 100 mg of protein per gram of body weight) in doses of 0.5 and 1.0 ml. Rectal temperature, respiratory rate and survival rate plus histopathological changes in liver, kidney, heart, and lung were evaluated. All treated mice died within 4 to 20 hours after inoculation, showing hypothermia, dyspnea and bradypnea. The kidney and liver were most affected organs, showing severe hyperemia, tissue degeneration and hyperplasia. The mice in the control group showed no visible abnormalities or death. The results showed toxicity and lethality due to the lysate macrocysts inoculum of Sarcocystis aucheniae in house mice.

KW - Inoculum

KW - Lethality

KW - Macrocystis

KW - Mouse

KW - Sarcocystis

UR - https://www.scopus.com/pages/publications/85002410357

U2 - 10.15381/rivep.v27i3.11988

DO - 10.15381/rivep.v27i3.11988

M3 - Artículo

AN - SCOPUS:85002410357

SN - 1682-3419

VL - 27

SP - 589

EP - 594

JO - Revista de Investigaciones Veterinarias del Peru

JF - Revista de Investigaciones Veterinarias del Peru

IS - 3

ER -

Toxicidad de Macroquistes de Sarcocystis aucheniae H. Wild en Ratones Domésticos (Mus musculus)

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